Projects

Research projects obtained in the hemato-oncology field:

1. Title: BCOR alterations and the activation of CXCL12 oncogenic pathway in classical Hodgkin lymphoma
PI: Prof. Maciej Giefing
Implementation period: 2022 – 2025
Granting institution: National Science Centre/OPUS 21
Funding: 1 768 146 PLN

2. Title: Identification of mTOR pathway deregulation mechanisms alternative to mutations in T-cell acute lymphoblastic leukemia (T-ALL)
PI: Natalia Maćkowska-Maślak. Msc.
Implementation period: 2022 – 2025
Granting institution: National Science Centre/PRELUDIUM 20
Funding: 209 950 PLN

3. Title: Functional analysis of novel oncomiR candidates in classical Hodgkin lymphoma
PI: Prof. Maciej Giefing
Implementation period: 2021 – 2024
Granting institution: National Science Centre/OPUS 20
Funding: 1 162 172 PLN

4. Title: cfDNA methylome analysis in Hodgkin lymphoma patients
PI: dr Kinga Bednarek
Implementation period: 2022 – 2025
Granting institution: National Science Centre Poland / SONATA
Funding: 935 618 PLN (212 000 Euro)

5. Title: Identification of genes and mechanisms underlying the recurrence of T-cell acute lymphoblastic leukemia
PI: Prof. Małgorzata Dawidowska
Implementation period: 2023 – 2027
Granting institution: National Science Centre/OPUS 24
Funding: 2 148 623 PLN

6. Title: Overcoming CAR-T cell exhaustion by modifying enhancers using CRISPR technology
PI: Karolina Rassek, Ph.D.
Implementation period: 2024-2027
Granting institution: National Science Centre Poland / Preludium22
Funding: 209 440 PLN

7. Title: CircRNAs involved in mechanisms of malignant transformation and relapse in T-ALL: towards new RNA-based therapies
PI: prof. Stefania Bortoluzzi (University of Padova – leader); prof. Małgorzata Dawidowska (IHG PAS); prof. Cristina Mecucci (Università degli Studi di Perugia); prof. Anke van den Berg (UMCG); prof. Panagiotis Ntziachristos (UGENT)
Implementation period: 2024-2029
Granting institution: AIRC – The Italian Foundation for Cancer Research
Funding: 542 280,20 Euro